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Stronger CYP3A4 inhibitors like ketoconazole or itraconazole may be predicted to have higher effects than observed with saquinavir. A starting up dose of twenty five mg of VIAGRA really should be thought of in individuals using erythromycin or robust CYP3A4 inhibitors (which include saquinavir, ketoconazole, itraconazole) [see DOSAGE AND ADMINISTRA